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Location

Berkeley, CA | United States

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Job description

Assistant/Associate Project Scientist mitochondrial unfolded protein response, stress, and aging Dillin Lab - Molecular and Cellular Biology

Position overview Position title: Assistant Project Scientist, Associate Project Scientist
Salary range: The UC academic salary scales set the minimum pay determined by rank and step at appointment. See the following table(s) for the current salary scale(s) for this position: . A reasonable estimate for this position is $82,900-$87,000.

Percent time: 100%

Anticipated start: Spring 2024

Position duration: One year with the possibility of extension based on performance and availability of funding.

Application Window
Open date: February 1, 2024

Most recent review date: Thursday, Feb 15, 2024 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Saturday, Mar 2, 2024 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

The department of Molecular and Cellular Biology at the University of California, Berkeley seeks applications for an Associate Project Scientist in the Dillin Lab, in the areas of mitochondrial unfolded protein response, stress, and aging.

The Dillin lab studies stress signaling and aging paradigms in C. elegans, tissue culture and mouse models. We are dissecting the signaling pathways between organelles, cells, tissues and organisms that contribute to stress resistance and aging phenotypes. We are looking to develop assays for stress and aging biology related to starvation and pharmacological induction of various stress response pathways.

The Project Scientist will develop assays focused on understanding how the mitochondrial unfolded protein response contributes to upregulation of specific stress responses and how these stress responses are communicated within a cell and extracellularly.

Key objectives include the development of new methods for studying the release of mitokine signals that activate the UPRMT, testing pharmacological interventions on disease and aging models, and developing new models using C. elegans genetics. Another objective is to study age-related disorders associated with defects in these signaling pathways. Other key questions involve the role intracellular organellar stress communication. Building on this we are aiming to develop theory on organelles communicating stress to each other, resulting in organismal alterations in stress resistance.

This position reports to Andrew Dillin, Professor. The department is interested in candidates who will contribute to advancing diversity, equity, inclusion, and belonging.

The incumbent will participate in background research, the analysis and interpretation of results; will prepare written and oral summary reports [internal and external]. The incumbent will also help to advise a group of junior researchers. The incumbent will attend and actively support scientific seminars, workshops, working team meetings and other venues for presentations of results and will develop and maintain collaborative research relationships; will pursue publication of research in peer-reviewed journals; and may pursue additional funding opportunities consistent with existing and future research programs and goals.

Lab :

Contract :

Qualifications
Basic qualifications (required at time of application)
PhD (or equivalent international degree)

Additional qualifications (required at time of start)
Seven years of post-degree research experience by start date
Publication record in peer reviewed journals

Preferred qualifications
Experience with aging biology, particularly mitochondrial response to stress by the release of mitokine signals that activate the UPRMT in C. elegans and cell culture.
Strong publication record in peer reviewed journals.
PhD in cell biology, biochemistry, molecular biology, genetics, genomics, or a related field.
Demonstrated expertise in cell biology, genetics, metabolism.
Expertise with methods such as confocal microscopy, mRNA-seq, CRISPR screens, protein biochemistry, qPCR, flow cytometry, measurement of cellular functions such as mitochondrial respiration and glycolysis, and genetic screens.
The ideal candidate is able to develop and troubleshoot new theoretical ideas and is enthusiastic about pursuing exciting and fundamental evolutionary theoretical questions.

Application Requirements

Document requirements

• Curriculum Vitae - Your most recently updated C.V.
  
• Cover Letter
  
• Statement of Research (Optional)
  
• Statement on Contributions to Advancing Diversity, Equity, and Inclusion - Statement on your contributions to diversity, equity, and inclusion, including information about your understanding of these topics, your record of activities to date, and your specific plans and goals for advancing equity and inclusion if hired at Berkeley. More Information and guidelines .
  (Optional)
  

Reference requirements

• 3-5 required (contact information only)

Apply link:



Help contact: [email protected]



About UC Berkeley


UC Berkeley is committed to diversity, equity, inclusion, and belonging. The excellence of the institution requires an environment in which the diverse community of faculty, students, and staff are welcome and included. Successful candidates will demonstrate knowledge and skill related to ensuring equity and inclusion in the activities of their academic position (e.g., teaching, research, and service, as applicable).


The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see:


In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.


As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.



Job location
Berkeley, CA





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About University of California Berkeley

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