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Scientist product development


Neurocrine Bioscience


Location

San Diego, CA | United States


Job description

Full job description

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

What We Do:

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company’s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson’s disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

About the Role:

Work with the Chemistry, Manufacturing, and Controls (CMC) project team to contribute and participate in early discovery through Phase 2a.


Provide formulation and analytical support for multiple preclinical programs.


Execute pre-formulation and preclinical formation development studies to support product advancement from early discovery through commercial.


Support the Product Development team through the following studies: thermodynamic and kinetic solubility, in-use stability, dose verification, toxicology formation development, high performance liquid chromatography (HPLC) method optimization and fit-for-purpose development, and other lead drug development candidates.


Prepare and evaluate formulations for administration in preclinical studies.


Perform chemical and physical stability studies focused on aqueous, organic, thermal and photo degradation.


Evaluate powder properties of Active Pharmaceutical Ingredient (API) and Drug Product (DP) intermediates to determine the potential impact on stage operations common in formation development.


Present drug development updates during department meetings, prepare author memorandums/reports, and deliver pharmaceutical talks on current and new techniques in support of early product development.


Source, procure, install, qualify, operate, and maintain instrumentation and pharmaceutical equipment required for pre-formulation and material science.


Participate in weekly and bi-weekly Product Development team meetings and report drug development progress, resource gaps, and timelines.

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Requirements:

How to Apply:

Interested candidates may email resumes to [email protected] referencing Job #YC-1112, or mail resumes to Neurocrine Biosciences, Inc., Attn: Donna Wright, Job #YC-1112, 12780 El Camino Real, San Diego, CA 92130.

Neurocrine Biosciences, Inc. is an EEO/AA/Disability/Vets employer.

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $86,200.00-$125,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.


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