Michigan State University
Location
East Lansing, MI | United States
Job description
The Medicinal Chemistry Facility is seeking a highly motivated and productive medicinal chemist to conduct daily research on exciting pilot projects for early- and mid-stage MSU drug discovery programs and focus particularly on the discovery and development of new anticancer agents. This individual will advance their medicinal chemistry expertise in a “Team Science” atmosphere with scientists of diverse expertise. The medicinal chemistry facility provides HTS triage, medicinal chemistry design, chemical biology, scale-up for in vivo studies and ADME support for ongoing programs. This individual will participate and will be trained in each of these activities. Successful candidates will report to the facility director, Dr. Edmund Ellsworth, and have regular interactions with Dr. Charles Hong, Chair of the MSU department of medicine.
Key functions:
• Apply, develop, and execute strategies in multi-step organic synthesis and purification of high-quality target molecules for biological screening.
• Adapt new technologies and solutions to support program studies.
• Work closely with medicinal chemistry facility director and other project team members in the design, syntheses, and optimization of compounds with improved potency, selectivity, together with improved ADME properties.
• Prioritize synthetic chemistry efforts to ensure timeline adherence and project alignment to meet the medicinal chemistry facility, project and university goals.
• Assist in the preparation of formal reports to project team, patents, publications, and project planning.
This position is for one year with potential for renewal.
Knowledge equivalent to that which normally would be acquired through completion of one or two years of post-bachelor degree work, such as a Master's in the specific field of research employment; one to three years of related and progressively more responsible or expansive work experience in research methodologies, writing reports, supervision, software, data interpretation and handling in area related to research being performed; or an equivalent combination of education and experience; and may require special licensing or certification in the field related to the area of employment.
Knowledge equivalent to that which normally would be acquired through completion of two years or more of post-bachelor’s degree work, such as a Master’s in the specific field of research employment; one to three years of related and with progressively with evidence of greater responsibility or expansive work experience in overseeing research projects and laboratory operations or the completion of a Ph.D. degree in organic chemistry with experience in the preparation of complex molecules. Additionally, the operation and maintenance of a variety of laboratory equipment, performing specialized and difficult analytical and research techniques, and designing research experiments would be considered a plus.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.
Provide 3 references knowledgeable of your work. Also, provide a research pictorial summary of your prior work experience / education.
STANDARD 8-5
This is an off-dated position funded for one year from date of hire with possible extension contingent upon funding renewal
About Michigan State University
Spartans work every day to advance the common good in uncommon ways.Together, we tackle some of the world?s toughest problems to find solutions that make life better?from alternative energy to better food safety to breakthrough medical and environmental applications achieved through rare isotope research.We teach. We explore and we discover. We collaborate and lead. We innovate, inspire, and empower. We achieve our potential and create circumstances that help our students and others achieve theirs.We're good at it, and we've been at it for more than 150 years.The nation?s pioneer land-grant university, MSU began as a bold experiment that democratized higher education and helped bring science and innovation into everyday life. The revolutionary concept became a model for the nation.Today, MSU is one of the top research universities in the world?on one of the biggest, greenest campuses in the nation. Home to nationally ranked and recognized academic, residential college, and service-learning programs, we?re a diverse community of dedicated students and scholars, athletes and artists, scientists and leaders.In ways both practical and profound, we work to create a stronger, more sustainable, and more hopeful future for all.
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