Investigator I - Analytical Chemist

Location

Silver Spring, MD | United States

Job description

Title: Investigator I - Analytical Chemist

Location: Silver Spring, MD

Status: FT

Travel: Negligible

Position Summary:

To address rapidly changing program needs across several ongoing research projects within the Division of Applied Regulatory Science (DARS), we require scientists with experience across several different scientific disciplines including bioanalysis, PK/PD, toxicology, immunology, microbiology, cell and molecular biology, mathematical modeling, and structure activity relationships to assist with these projects.

Duties/Responsibilities:

• Developing and validating chromatographic and mass spectrometry-based assays for small molecules in various biological matrices like plasma, serum, dry blood spots etc.
• Developing and validating ligand binding assays for various protein molecules.
• Produces reports for reliable, sensitive, and validated methods of analyses (prepares, edit, and designate project reports).
• Bioanalytical support for the in-vitro studies of the division includes method development, validation, sample analysis and data sharing.
• Coordinate the calibration of instruments like HPLC, LC-MS/MS and other laboratory instruments.
• Preparation of standard operating procedures (SOP) and protocols for method validation and pharmacokinetic/tissue distribution/toxicity study sample analysis.
• Revises existing SOPs and originates new documentation.
• Ensures that all work follows all pertinent Standard Operating Procedures, Good Laboratory Practice, and safe work practices.

Minimum Requirements:

• D. in Analytical Chemistry, Chemistry (General), Physical Chemistry, Life Health and Medical Sciences, Biochemistry, or any other related field with 2+ years of laboratory experience with mass spectrometry and the ability to work independently.
• Experience in developing and validating analyses for small molecules, biologics, and proteins by LCMS.
• Knowledge of basic laboratory safety training is advantageous but not required.
• Basic office software skills (Word, Excel, PowerPoint, Sigmaplot, Access or FileMaker Pro databases etc.) are required and basic statistical data analysis skills are highly desired.
• Exceptional oral and written communication skills and ability to network and build consensus within a multi-disciplinary organization.
• Drug regulatory experience is desired, particularly regulatory science research.

Apply online at our website:

Disclaimer: This is not to be an exclusive list of all responsibilities, duties, and skills required of the person in this job. KIC is an Equal Opportunity Employer. KIC considers all applicants for employment without regard to race, color, sex, national origin, religion, age, physical or mental disability, family responsibility, marital status, sexual orientation, political affiliation, veteran's status, or any other legal protected status. Pursuant to The Alaska Native Claims Settlement Act 43 U.S.C. Sec. 1601 et seq., and federal contractual requirements, Kikiktagruk Inupiat Corporation, may legally grant certain preference in employment opportunities to KIC Shareholders and their Descendants. EOE/AA/M/F/D/V. Please view Equal Employment Opportunity Posters provided by OFCCP here . Successful candidate must pass, comply, and adhere to KIC's Drug and Alcohol policy/testing requirements and pass a thorough background check including fingerprinting .

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