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Bioinformatics Manager | University of California San Diego


University of California San Diego


Location

La Jolla, CA | United States


Job description

This is a UC San Diego Internal Recruitment open to UCSD and UCSD Health System Staff Only

UCSD Layoff from Career Appointment : Apply by 02/01/2024 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants : Apply by 02/06/2024. Eligible Special Selection clients should contact their Disability Counselor for assistance.

This position will work a hybrid schedule which includes a combination of working both onsite at La Jolla and remote.

DESCRIPTION

The UCSD Department of Radiology offers challenging career opportunities, cutting-edge research, and state-of-the-art services for clinical and translational studies.

The Center for Multimodal Imaging and Genetics (CMIG) is a multi-disciplinary group of scientists, programmers, and support staff that plays a leading role in several national and multinational initiatives involving collection and analysis of imaging, genetic, and behavioral data from healthy participants and patient populations.

CMIG serves as the data core for two large-scale longitudinal NIH funded studies with developmental populations. The Adolescent Brain Cognitive Development (ABCD) study follows ~12,000 children with longitudinal neuroanatomical, functional imaging, and behavioral assessments across 21 sites within the US. The major goals of the study are to provide a publicly available data resource to examine the relationships between environmental influences -- including substance use -- and adolescent brain and cognitive development. The Healthy Brain and Child Development (HBCD) Study is a large-scale longitudinal study of the brain, cognitive, and emotional development that will follow mothers and their children from before birth through the first decade of life. The project will involve over 7,000 families at 25 sites across the United States and aims to better understand which harmful and protective environments exert the greatest impact on child development.

The Bioinformatics Supervisor will serve as Co-Director of the Data Analysis, Informatics & Resource Center (DAIRC) of the ABCD Study. In this role, they will oversee all efforts of the center related to management of the ABCD data resource, including data capture, ingestion, processing, quality assurance, monitoring, and reporting as well as curation for public data releases. The incumbent will lead the DAIRC teams for REDCap data capture development and data science/management and supervise the work of the DAIRC Associate Directors and their teams as it relates to above goals. They will coordinate with the ABCD Coordinating Center (CC) to achieve the scientific, administrative, and budgetary goals of the study.

In coordination with Principal Investigators (PIs), co-investigators, and staff researchers, the Bioinformatics Supervisor will develop and manage a data curation plan for quality control of the high-dimensional dataset collected in the context of the nationwide study. They will supervise the design and implementation of database systems for the storage and curation of the collected data, including the development of data ingestion routines, processing pipelines, and ETL workflows, as well as develop methods and procedures to proactively identify dataissues. Furthermore, they will spearhead the development and maintenance of the infrastructure for annual data releases and oversee the development of web applications for data download, interactive data exploration, and the analysis of data released in public data releases, in coordination with the NIH Brain Development Cohorts Data Sharing Platform, and associated contractors.

The Bioinformatics Supervisor will lead the design, testing, and maintenance of data capture instruments for the ABCD Study using the electronic data capture system REDCap. They will work closely with the leadership and domain experts in the ABCD consortium to develop and implement protocols, processes, and timelines for data collection, data review and correction, and preparation of the dataset for public data release. The incumbent will further lead the design, development, and adaptation of web applications/dashboards and automated reports used by ABCD leadership and personnel to monitor performance indicators like visit missingness / retention, protocol completeness, data quality, and other relevant metrics.

The Bioinformatics Supervisor will also play a prominent role in the HBCD Data Coordinating Center (HDCC). In coordination with the HBCD Consortium Administrative Core (HCAC) and other groups within the HDCC, they will oversee the design, development, and adaptation of web applications/dashboards to support the results-based accountability efforts of the HBCD

About University of California San Diego

UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.

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