The University of North Carolina at Chapel Hill
Location
Chapel Hill, NC | United States
Job description
Vacancy ID: PDS004087
Position Summary/Description:
One postdoctoral associate position is available in a cancer research lab located within the University of North Carolina at Chapel Hill Lineberger Cancer Center. The lab currently studies the hypoxia signaling, prolyl hydroxylases, and cancer, specifically breast and renal cell carcinoma. One project focuses on using novel proteomic and genomic approaches to screen for novel prolyl hydroxylase substrates that play important roles in various of cancer. The other project involves integrating ChIP-seq strategy with gene expression profiling to identify EglN2 prolyl hydroxylase and Hypoxia-inducible factor 1 (HIF1) targets in the malignant diseases. The ultimate goal is to understand mechanistically how oxygen-sensing pathways contribute to cancer progression, which will facilitate our design of an effective treatment strategy to target cancer specifically. Besides these major research directions, we are also interested in studying the mechanism of chromosomal instability in cancer, specifically related to FBW7 tumor suppressor pathways.
Education and Experience:
Strong background in molecular/cell biology, biochemistry, and cancer biology.
About The University of North Carolina at Chapel Hill
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.
Connections working at The University of North Carolina at Chapel HillJob tags
Salary
