Location
Bethesda, MD | United States
Job description
Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).
Overview
Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Biologist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Research Center (VRC), Vaccine Production Program(VPP).
Responsibilities - Develop viral vaccines, recombinant proteins and/or virus-like particles or monoclonal antibodies.
- Perform investigations and documentation of cell line growth, optimization of cell culture/fermentation conditions, cell culture technology development, improvement of cell culture platforms, modeling of cell culture behavior, troubleshooting of cell culture/fermentation processes, and tech transfer of defined cell culture/fermentation processes to the clinical production facility.
- Capture process descriptions and results in lab notebooks, tech transfer documents, and technical reports.
- Independently set-up and operate bioreactors and other cell culture equipment required while executing development studies.
- Participate in project and laboratory meetings, keep current with compliance obligations, and be responsible for maintenance of the laboratory and equipment.
- Contribute results and studies for publication in peer reviewed journals.
- Serve as an SME/functional lead in pDNA (microbial) process development.
- Support VRC mRNA program through fermentation process evaluation, optimizations and material generation.
- Provide training on equipment, processes, and microbial techniques.
- Provide support for lab operations initiatives, including:
- Consumables forecasting, materials inventory monitoring and supply.
- Equipment maintenance and support (Nova Flex2 Analyzers).
- Standardize process operations across projects/scale: authoring SOPs and provide SME direction.
- Serve as SME in setup, use, and maintenance of bioreactor control monitoring systems, including Lucullus or equivalent hardware/software
- Provide end-user trainings.
- Author protocols and other guidance documents.
- Liaise with NIAID IT to ensure robust performance and troubleshoot operational issues as needed.
Experience Required / Requirements - B.S. in Biology, Chemistry, Chemical Engineering, Bioengineering, or related life science degree
- 5-10 years of industry-level experience in cell culture development
- Experience with tech transfer of cell culture processes to manufacturing is required
Benefits - 100% Medical, Dental & Vision premium coverage for Employees
- Paid Time Off (Including Holidays)
- Employee Referral Bonus
- 401K Match
- Tuition reimbursement and professional development opportunities
- Flexible Spending Accounts:
- Healthcare (FSA)
- Parking Reimbursement Account (PRK)
- Dependent Care Assistant Program (DCAP)
- Transportation Reimbursement Account (TRN)
The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.
Accessibility: If you need an accommodation as part of the employment process please contact:
[email protected]
Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.
Job tags
Salary