University of Arizona
Location
Tucson, AZ | United States
Job description
Postdoctoral Researcher, Alzheimer’s Disease, College of Medicine, Department of Neurology, University of Arizona, Tucson, USA
Who are we
Dr. Chang’s lab in the department of Neurology at the University of Arizona is seeking a motivated postdoctoral researcher to develop novel therapeutics for Alzheimer’s disease and other neurodegenerative diseases. Chang lab is well funded by NIH for developing novel treatments for neurodegenerative diseases, healthy aging, and cancer using the most cutting-edge integrated approaches driven by Artificial Intelligence (AI) and wet lab benchwork.
Position description
The successful applicant will work as a member of a collaborative research team to develop potential drugs using state-of-the-art in vitro and in vivo methodologies. This project involves both human brain cell models and animal models of Alzheimer’s disease. Research will also require development of in vitro assays, co-culture and/or brain organoid and in vivo experimental paradigms as warranted by progress on the project, a willingness to work collaboratively with both bench and computational scientists, preparation of research results for publication in top-tier peer reviewed journals and presentation of data at scientific meetings. The position will also involve research mentorship of graduate students and/or undergraduate research assistants. An extensive working experience in neurodegenerative diseases and/or neuropharmacology as well as animals’ models, and a background in neurobiology/molecular biology is preferred. Previous experience with in vivo models of Alzheimer’s disease, genetic approaches (i.e., siRNA, CRISPR/Cas9), iPSC-derived CNS cell co-cultures and/or brain organoid, and microscopy is preferred. Experience with animal behavior is a plus. Previous working experience with Mesoscale Discovery (MSD) assay is strongly appreciated.
Duties and Responsibilities
*Independently design, perform and interpret experiments.
*Prepare research results for publication in a timely manner.
*Present data at scientific meetings.
*Supervise graduate and undergraduate students working on the project.
*Assist with administrative and maintenance duties in laboratory management.
*Attend lab meetings.
Qualifications
-PhD or MD/PhD in Molecular biology, Neuroscience or Biomedical sciences.
-Research experience in neurodegenerative diseases or neuroscience laboratory.
-Research experience with animal models
Preferred Qualifications
-Working experience in neurodegenerative diseases
-Hands-on experience in Mesoscale Discovery assays and microscope
-Previous experience with in vivo models of Alzheimer’s disease,
-Previous experience in genetic approaches (i.e., siRNA, CRISPR/Cas9)
-Previous experience in iPSC-derived CNS cell co-cultures and/or brain organoid development.
-Experience with animal behavior.
Benefits
-Competitive salary
-Outstanding UA benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; access to UA recreation and cultural activities; and more!
-This position is eligible for visa sponsorship
-The position is eligible for immigration supports upon approval by Dr. Chang and institution.
To Apply
This position is open immediately. To apply, please submit a cover letter and curriculum vitae and contacts of at least three references to Dr. Rui Chang ([email protected]) . The cover letter should detail the applicant’s most significant scientific experiences and the most comfortable skillsets that are relevant to this position.
Job Type: Full-time
Pay: $55,000.00 - $70,000.00 per year
Benefits:
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Work Location: In person
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