R&D Chemist

Location

Indianapolis, IN | United States

Job description

Full Spectrum Lab Services from CBRE offers a professional suite of services to a variety of clients in the life sciences industry, including those in pharmaceuticals, biotech, medical devices, and genomics, as well as contract research organizations (CROs) and contract manufacturing organizations (CMOs).

Our comprehensive range of services includes laboratory consulting, real estate services, instrumentation repair and maintenance, full asset management, and more—covering the entire spectrum of life sciences facilities. With expertise across various life sciences categories, CBRE is a leader in managing highly-regulated spaces within the industry.

About the role!

As a laboratory scientist in the SMDD biosynthetic drug substance development group, you will help with the chromatography process development for early and late phase peptides/proteins as well involvement in the development of new purification/chromatography technologies.

This position is for an experienced chemist possessing in depth technical knowledge to perform multiple laboratory functions and various types of laboratory analysis. Instrument integration with automated data analysis workflows and process sampling interfaces.

A strong scientific or chemical engineering foundation is a prerequisite for this role. In addition, the ability to exhibit a high level of attention to detail and good record keeping is essential. Maintaining accurate records and interpreting data to provide detailed information and analysis on the execution of experiments will be a daily activity.

What you'll do!

• Conduct routine analyses in compliance with applicable methods, protocols, SOPs, and regulatory agency guidelines.
• Analytical support and Method development of both quantitative and qualitative HPLC methods
• Preparative HPLC purification/isolation of process impurities and degradation products
• Analytical instrument maintenance: Support minor instrument repairs, setup, software troubleshooting, and/or routine maintenance of LC and UPLC/MS equipment and preparation of laboratory reagents
• Data analytics: Operation of a variety of instrumentation to generate comprehensive and high-quality analytical results. 
• Instrumentation may include Liquid handling systems, HPLC, preparative HPLC, UPLC, Gas Chromatography, Mass spectrometers.
• AKTA automated liquid chromatography for purification of proteins and peptides.
• AKTA Unicorn, Waters Empower and electronic notebooks.
• Fluorescence Spectroscopy
• LC-MS analysis in support of synthetic molecule development and interpretation of results.
• Ensure project deliverables are scientifically accurate and meet timeline expectations.
• Comply with all laboratory Safety guidelines including Personal Protective Equipment (PPEs).
• Maintain general cleanliness of the lab, including personal bench space and common-use areas, and maintain laboratory supplies.
• Participates in required training activities.
• Perform method analysis and development with quick turnaround times.
• Document laboratory work appropriately in laboratory notebooks and/or technical reports.

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