Location
Cambridge, MA | United States
Job description
The Role:
Moderna is seeking a highly motivated bioinformatician with experience in mass-spectrometry based immunopeptidomics and proteogenomics to join our highly collaborative, multi-disciplinary, and fast-paced team. The primary focus of this position is to apply bioinformatics tools and establish computational pipelines for mass spectrometry data analyses and integration with other data modalities (genomics, transcriptomics). The successful candidate will work closely with computational biologists, immunologists, and translational biologists in Oncology Research to support target discover, translational research, and clinical development.
Here’s What You Will Do: Utilize and develop bioinformatics solutions for the analysis of large-scale mass spectrometry experiments (DDA and DIA), focusing on the identification and quantification of MHC-bound peptides (immunopeptidomics).
Explore, evaluate, and analyze external (e.g. PRIDE) and internal immunopeptidomics and immunogenomics datasets to support therapeutic target discovery and validation
Interpret complex datasets to drive biologically relevant findings in the context of immunopeptidomics
Collaborate closely with cross-functional research teams to design experiments and refine data acquisition strategies for improved data quality
Maintain detailed documentation of data analysis methods and results
Participate in team meetings and present findings
Stay abreast of the latest developments in mass spectrometry data analysis and bioinformatics approaches.
Here’s What You’ll Bring to the Table: Master's degree + 3 years of experience in Biochemistry, Chemistry, Bioinformatics, Computational Biology, or a related field. PhD degree is a plus
Rigorous understanding of mass spectrometry concepts and techniques, including the principles and application of data-dependent acquisition (DDA) and data-independent Acquisition (DIA) methods
Previous hands-on experience with mass spectrometry data analysis software, especially when applied to immunopeptidomics, and the familiarity with the role of MHC molecules in antigen presentation
Experience with RNA-seq and WES data
Strong coding skills in Python and/or R
Experience with high performance cloud computing such as the AWS cloud computing platform
Strong analytical, problem-solving, and communication skills
Ability to work independently as well as part of a collaborative research team.
Strong organizational skills with the ability to manage multiple tasks and meet deadlines.
Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:
Highly competitive and inclusive medical, dental and vision coverage options
Flexible Spending Accounts for medical expenses and dependent care expenses
Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
Family care benefits, including subsidized back-up care options and on-demand tutoring
Free premium access to fitness, nutrition, and mindfulness classes
Exclusive preferred pricing on Peloton fitness equipment
Adoption and family-planning benefits
Dedicated care coordination support for our LGBTQ+ community
Generous paid time off, including: - Vacation, sick time and holidays
- Volunteer time to participate within your community
- D iscretionary year-end shutdown
- Paid sabbatical after 5 years; every 3 years thereafter
Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
401k match and Financial Planning tools
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Complimentary concierge service including home services research, travel booking, and entertainment requests
Free parking or subsidized commuter passes
Location-specific perks and extras!
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at
[email protected] . (EEO/AAP Employer)
-
Job tags
Salary
