Senior Scientist I, Biologics Drug Product Development

Location

South San Francisco, CA | United States

Job description

The Biologics Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept.

We have an exciting opportunity for a Senior Scientist I to join our team at our Bay Area site in South San Francisco, CA.

KEY RESPONSIBILITIES INCLUDE:

• Develop stable and fit-for-purpose liquid and lyophilized drug products through the design and execution of formulation, process development, and clinical in-use studies.
• Support testing of representative stability lots to support drug substance and drug product shelf-life extension.
• Generate high-quality data based on sound scientific principles and document results in electronic lab notebook.
• Prepare scientific presentations, technical reports, and regulatory documents.
• Drive innovation and continuously enhance capabilities and business processes within the organization.
• Work efficiently and collaboratively in an agile team setting with minimal direction from supervisors.
• Represent the function within cross-functional and cross-site technical teams.

QUALIFICATIONS:

• Ph.D. in chemical engineering, pharmaceutical sciences, material science, analytical sciences or equivalent field with 0-3 years of experience or BS/MS degree with 8-10 years of relevant experience in the biotechnology or pharmaceutical industry.
• Strong technical background in protein formulation principles, drug product degradation pathways, and characterization approaches.
• Deep technical understanding in lyophilization is desired.
• Hands-on experience in analytical techniques used for protein characterization and stability testing preferred (e.g., SEC, CE-SDS, icIEF, HIAC, MFI, DLS, etc.).
• Prior experience in the development of protein product formulations is highly desirable.
• Detail-oriented and highly organized with a demonstrated ability to drive innovative science and solve complex problems.
• Excellent communication and written skills

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in  good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual  compensation paid within this range will depend on many factors including geographic location, and we may ultimately  pay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision  insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable.  The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits  that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and  may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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Salary