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Location

New Haven, CT | United States

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Job description

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC targeted protein degraders, that are designed to harness the body's own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins. In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and "undruggable" targets, the company has three investigational clinical-stage programs: ARV-766 and bavdegalutamide for the treatment of men with metastatic castration-resistant prostate cancer; and vepdegestrant (ARV-471) for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer. Arvinas, as part of its overall business strategy, selectively assesses opportunities for potential collaboration, license, marketing and royalty arrangements, and similar transactions, to advance and accelerate the development and enhance the commercial potential of its product candidates.


#TeamArvinas is made up of approximately 450 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company's values and mission - to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC® protein degradation platform. We're really excited about the work we're doing inside and outside of Arvinas, and think you will be, too. But don't just take our word for it - learn more about life at Arvinas and what employees have to say .


For more information, please visit .

Position Summary


Arvinas has an outstanding summer internship opportunity for the selected student to contribute to two projects.


The first project is focused on the standardization and performance verification of liquid handling instruments (Agilent's Bravo) across research organizations.

• This project will assist Arvinas in the establishment of best practices for maintaining our capital assets. It contributes to extending the useful life of our equipment, reduces maintenance spend and increases the quality of the data being produced.

The second project is to assist in enabling and expediting high throughput screens for targets of interest.

• This project will assist Arvinas with research by executing assays more quickly, safely and with a higher level of data quality.

This position reports to the Director of Lab Asset Management and Automation is based in New Haven, CT.

Principal Responsibilities


Key responsibilities of this role include, but are not limited to:

• Liquid Handler Project:
  • Export, implement and train end-users on the Agilent, Bravo liquid handler "Performance Verification" protocol across all Arvinas organizations.
  • Export, implement and train end-users of the Agilent, Bravo liquid handler on the "optimal mixing" parameters across all Arvinas organizations.
  • Migrate Bravo protocols from the current version of VWorks software into version 14.X which is being installed on all machines.
• High Throughput Screening Project:
  • Assist in the transfer of bench assays onto the automated platform.
  • Perform parameter testing. This work includes time-course studies, data collection/analysis, and the presentation of the results.
  • Assist in the determination of the stability of reagents.
  • Development of optimized compound concentration for a specific assay.
  • Establishing biological relevance between the manual and automated processes i.e. the qualification of bench shaking verses orbital shaking associated to the integrated robotic system.

Qualifications

• Experience in a research lab (academic or industry); familiarity with general lab instrumentation, familiarity with the Bravo liquid handler is a plus. Adept using Excel, Word, and PowerPoint. The ability to work independently with minimal oversight as well as on a team.

Education

• Preference to a rising senior in an engineering undergraduate program or a student that has been accepted to or is in master's engineering or bioengineering program.

#LI-Remote


Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit


Arvinas is an Equal Opportunity Employer

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