Location
Indianapolis, IN | United States
Job description
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
The Research Team within the Lilly Diabetes, Obesity, and Complications Therapeutic Area is dedicated to advancing the field by focusing on the exploration and preclinical development of novel therapeutics targeting Atherosclerotic Cardiovascular Disease (ASCVD) and Obesity. We are actively seeking an experienced in vitro biologist to lead the development, validation, and execution of in vitro and cell-based pharmacology assays for ongoing drug discovery initiatives. The ideal candidate will possess a demonstrated proficiency in implementing in vitro assays, consistently adhering to detailed protocols, and delivering comprehensive data assessments. Collaboration is key, as the selected candidate is expected to work closely with the ASCVD, Obesity, and Incretin Discovery groups within a team-oriented environment, providing expertise and support to other groups as required.
Responsibilities - Apply innovative automation to enable compound screening in 384-well assay format or greater. Experience with multidrop liquid dispenser, echo liquid handler, is preferred.
- Critically evaluate data using NGR data analysis software.
- Perform cell culturing and molecular biology/biochemistry techniques, including nucleic acid transfection, stable or transient cell line generation and evaluation, and gene expression profiling (qPCR).
- Design and perform assays within the field of receptor pharmacology, encompassing tasks like receptor binding and functional cellular readouts, including cAMP, phosphorylation, calcium, and other relevant biomarkers. Additionally, employ molecular biology techniques such as ELISA, SDS-PAGE, and Western blotting.
Basic Qualifications
- Bachelor's or Master's degree in biology or a closely related field
- Atherosclerotic Cardiovascular Disease (ASCVD) and/or Obesity drug discovery experience
Additional Skills/Preferences
- Experience and willingness to work with radioisotopes, chemical, and biological hazards.
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources (
[email protected] ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
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