Senior Scientist - DMPK

Location

Lexington, MA | United States

Job description

About the Department

Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our greater Boston R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

 
The team is comprised of collaborative, diverse and passionate people who have a true sense of pride in their work and are committed to helping others grow and develop their careers. You’ll also have a platform to engage with key stakeholders on a global scale throughout the entire pipeline process. And while changing the future of diabetes, obesity and MASH is no easy task, we also recognize the importance of an enjoyable workplace, which is why we’ve cultivated a culture of fun, ingenuity and innovation. And our competitive compensation package and support of a healthy work-life balance all add to a best-in-class employee experience. We are changing lives for a living. Are you ready to make a difference?

The Position

The Sr. Scientist will provide scientific leadership in the discovery of small molecule drug candidates by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas. This will be achieved by proposing and leading internal and external research efforts to support project goals. The Sr. Scientist will work closely with pharmacology and medicinal chemistry team, lead DMPK efforts to optimize molecules across a variety of therapeutic areas utilizing in vitro, in vivo, and in silico methods and models to generate novel chemical matter with drug-like properties. The sr scientist will collaborate with outsourcing managers to identify and manage CROs with specialized ADME capabilities, and build and maintain relationships with global Novo Nordisk ADME experts to leverage expertise and harmonize ADME strategy. The individual will be seen across the company and beginning to be viewed externally as a method/subject expert within small molecule DMPK

Relationships

Reports to the head of the DMPK department at Novo Nordisk.

Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at NNRCSI; & frequent interaction with project managers & other colleagues across global R&D. Individual may direct the work of other staff members.

Individual will interact with external research collaborators both academia- & industry-based.

 

Essential Functions

• Propose, plan, and execute complex, diverse projects that require a strong scientific understanding of research area
• Provide expert-level guidance to experimental plans and data interpretation
• Troubleshoot highly complex tasks through independent and team-based efforts
• Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
• Plan and analyze in vitro & in vivo experiments
• Make independent decisions related to day-to-day experimental activities
• Assume responsibility for project design, implementation, and interpretation
• Analyze complex data with high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
• Ensure proper documentation of all experiments and data
• Collaborative teamwork
• Function as project leader for global, cross-functional experimental teams to achieve project goals
• Communicate regularly with international colleagues within Novo Nordisk
• Indirectly supervise and provide mentorship to Research Assistants, Associates, & junior Scientists
• Actively participate in cross-functional teams and meetings to drive project success
• Achieve business goals, share learnings, knowledge and skills & promote cross-functional teamwork
• Share knowledge & expertise to expand team capabilities and goals
• Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
• Recommend, present, and champion new targets or methodologies
• Write and review collaborative research manuscripts, project documents, and milestone documents
• Complete assignments requiring expert-level knowledge of techniques and practices related to the research area
• Represent the organization as NN-subject matter expert by attending and presenting at scientific conferences and global meetings

Qualifications

• Bachelor 's degree within subject matter expertise required
• 18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree in with 6+ years’ post-doctoral and/or industry relevant experience can be considered
• Relevant required experience includes: Excellent understanding of ADME principals with knowledge of PK modeling or biotransformation highly desirable
• Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced models
• Demonstrates excellent verbal and written communication skills.
  
   

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.

Job tags

Salary