Chemical immunology - Chemist I/II

Location

Germantown, MD | United States

Job description

This position will be responsible for interface between chemistry and immunology teams designing, synthesizing, and evaluating efficacy of SNAP-TI peptide antigen nanoparticle system in preclinical autoimmunity models. A strong chemistry background is required with familiarity of organic synthesis techniques, with some familiarity with T cell immunology a benefit. The candidate will work as part of a multi-disciplinary team of chemists, immunologists, and engineers. The role will be partially laboratory-based, but there will be opportunities for planning, presentation, and strategy with acquired experience.

Key responsibilities include

• Design of peptide antigen drug conjugate nanoparticles and corresponding preclinical animal studies to evaluate efficacy in models of autoimmunity
• Synthesis and purification of peptide antigen conjugate nanoparticles (lab based)
• Analyze acquired data, synthesize findings, and recommend next steps in regular written and oral presentations

Essential knowledge, experience, and skills

• BS, MS, or PhD in chemistry, immunology or related discipline with salary commensurate with experience
• At least 2 years of lab experience related to chemical immunology preferably including:
• Organic synthetic chemistry, HPLC, LC-MS and prep-HPLC (required)
• Peptide synthesis and purification (required)
• Nanoparticle characterization (preferred)
• T cell stimulation assays (preferred)
• The ability to work collaboratively in a dynamic team environment
• Experience in data management, analysis, and presentation

Compensation

• Salary commensurate with experience ($65,000–$105,000)
• Additional benefits include employer-funded health, dental and vision insurance; 401k retirement plan; career development opportunities, and paid time off (PTO).

Job tags

Salary

$65k - $110k