Senior Scientist

Location

Maryland | United States

Job description

Established in 2004, Culmen International is committed to enhancing international security, strengthening homeland defense, optimizing government operations and providing humanitarian assistance around the world. We provide technical and management expertise, develop innovative technology solutions, and deliver youth care services, logistics, training and language services worldwide. With experience in over 126 countries, Culmen supports our clients to accomplish critical missions in challenging environments.

Culmen International is hiring Senior Scientists  to provide support for the Walter Reed Army Institute of Research Experimental Therapeutics Program (WRAIR ET) and will be onsite in Silver Spring, Maryland. 

Experimental Therapeutics (ET) is a drug discovery and development enterprise created to protect military personnel from death, disease, and injury and meet Army and DOD mission requirements. While its historical focus has been radioprotection and parasitic disease, ET applies its core competencies of medicinal, synthetic, and analytical chemistry as well as clinical pharmacology to all therapeutic areas within the Medical Research and Development Command's portfolio. ET has a 75-year legacy of excellence in small molecule drug development, with over 65 Investigational New Drug (IND) applications submitted to the U.S. Food and Drug Administrations (FDA). 

• Lead in vitro testing for the Combating Antibiotic-Resistant Bacteria (CARB) group
• Lead, guide, and coordinate efforts within a multidisciplinary research group to execute in 
  vitro and in vivo studies aimed at developing antibacterial small molecule drugs to prevent 
  and/or treat complex wound infections in a prolonged care environment 
• Collaborate with in vivo team partners to assess potential efficacy of antibacterial small 
  molecule drugs using the neutropenic mouse thigh infection model 
• Design and implement in vitro HTS assays (MIC, synergy) involving robotic liquid handlers to 
  screen compound and large (~100 strains) bacterial libraries
• Collect and analyze large datasets using analytical software to make detailed observations and 
  meaningful interpretations of the results
• Communicate regularly with government and industry collaborators through written reports 
  and oral presentations to provide project updates and conclusions of research findings 
• Prepare and finalize scientific documentation such as grants, SOPs, and tech transfer forms

• Master's Degree biological sciences or equivalent. 
• 6+ years of relevant experience 
• Demonstrated experience in leading projects (personnel and research efforts), submitting proposals for research efforts, and performing data analysis and reporting.
• Demonstrated subject matter expertise in design, development, validation, and performance of in vitro assays for antimicrobials, antivirals, and/or antibacterial drug development.
• Demonstrated expertise with liquid-handling robotics, tissue culture, aseptic technique, and high content imaging.
• Demonstrated expertise handling BSL 1 and 2 infectious agents, toxic chemicals, and blood-borne pathogens.

• Ph.D.

• Exceptional Medical/Dental/Vision coverage with 100% of the premiums paid by the company for all employees and their eligible dependents
• 401k – Vested immediately and 4% match
• Life insurance and disability paid by the company
• AFLAC Available
• Tuition Assistance
• 12 Paid Holidays

At Culmen International we are committed to creating, promoting, and sustaining a culture of diversity, equity, and inclusion. Our commitment to these values is unwavering across all our work around the world. We include and celebrate employees of diverse races, genders, religions, sexual orientations, ethnicities, nationalities, socioeconomic statuses, languages, (dis)abilities, ages, and religious commitments. These differences drive innovative solutions to meet the needs of our employees and clients. Culmen is an equal opportunity employer.

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