Location
England | United Kingdom
Job description
About Our Client
Our client is an early-stage biotechnology startup merging artificial intelligence (AI) and advanced high-throughput TCR screening techniques to revolutionise the treatment of solid cancers. Their pioneering AI platform is poised to design high-affinity and specific T-cell-receptor (TCR) based therapies.
Job Description
As a Research Associate, you will be responsible for:
- Collaboratively designing and characterising TCRs for pipelined and new disease targets.
- Conducting multiple protein science operations, including expression, purification, and biophysical analysis.
- Tackling molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
- Managing tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
- Drafting, revising, and overseeing lab protocols.
- Offering essential lab support and upholding facility upkeep.
The Successful Applicant
Candidates for this role will be expected to have:
- A PhD in Immunology, Cell Biology, Biochemistry, or related field, with at least 2 years of relevant laboratory experience.
- Knowledge of basic molecular biology protocols, with an emphasis on cloning and PCR.
- A background in protein expression, purification and biophysical characterisation.
- Experience in Bioorthogonal chemistry and bioconjugation.
- Experience in lipid nanoparticle formulation.
- Experience cell and immunological assays (flow cytometry, ELISA etc.)
- Experience NGS analysis pipeline (specifically data analysis using software such as R)
- SOP documentation experience.
What's on Offer
- A competitive salary in the range of £35,000 - £45,000 per annum.
- Generous holiday leave policy.
- Access to their fully-equipped private lab within a state-of-the-art complex.
If you're an agile learner-someone who thrives in collaboration, who welcomes challenges with optimism, sharing a passion for the intersection of AI and novel TCR therapies in an ever-growing biotech industry, then this is certainly the perfect role for you. #J-18808-Ljbffr
Job tags
Salary