Immunocore
Location
Abingdon, Oxfordshire | United Kingdom
Job description
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. You will work with outstanding people who together pioneer the research, development and commercialization of bi-specific TCR therapies. We aim to create an environment where individual contributions and initiatives can be maximized, while fostering a culture of collaboration, based on respect and integrity. We want each individual employee to own their career, as part of high-performing teams, and in the context of on-the-job and formal continuous development and training, as well as constructive feedback. We always strive to identify ways to improve what we do and how we do it, by asking questions, voicing opinions, exploring various approaches and staying connected with healthcare professionals, patients, academia and other key partners.Key Responsibilities
Key Responsibilities The role:
We are looking for a collaborative and enthusiastic NGS scientist to join our Protein Engineering team. You will be working closely with a Senior Scientist and colleagues across R&D to contribute to the Immunocore’s TCR discovery and engineering process. The role is laboratory based and involves processing samples to generate NGS libraries for sequencing on Illumina and/or Nanopore platforms. A strong interest in application of newest sequencing approaches is a key requirement.
Key responsibilities:
• Provide ongoing NGS support for pipeline and R&D projects
• Prepare libraries for sequencing following established protocols
• Plan and design experiments with instruction and guidance from manager
• Independently or in team, test and introduce new methodologies
• Help define and write SOPs
• Maintain the NGS laboratory (equipment, reagents, consumables, safe working practices)
• Keep detailed records of research activities
• Analyse and report results of experiments in writing and in meetings
• Actively participate in team meetings and lab organisation
Experience and Knowledge:
• Essential
• Extensive experience in library preparation (Illumina and/or Nanopore) and understanding of Next-Generation Sequencing technologies
• Experience in primer design and PCR troubleshooting
• Experience in basic molecular biology techniques such as nucleic acid extraction and quantification, PCR, (RT-)qPCR, agarose gel electrophoresis, molecular cloning
• Ability to design, execute and interpret experiments to address relevant scientific questions
• Strong team player with good communication skills, high attention to detail and good time management
• 1+ years of research experience in industry or academia
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