Location
Sheffield | United Kingdom
Job description
We are seeking an independent and motivated postdoctoral Research Associate to work on an MRC-funded project at the
interface of developmental/stem cell biology and disease modelling. The successful applicant will primarily employ human
pluripotent stem cell (hPSC) differentiation and genetic engineering to elucidate the nature of human enteric nervous
system (ENS) progenitor dynamics and their crosstalk with Schwann cell precursors during ENS development and
Hirschsprung disease. This project is a close collaboration with the group of Conor McCann at the UCL Great Ormond Street
Institute of Child Health in London.
Applicants must hold a PhD (or be close to completion/have equivalent experience) in a subject related to stem
cell/developmental biology. Experience in hPSC culture and neural/neural crest differentiation, immunocytochemistry, flow
cytometry and qPCR is required. Good knowledge of CRISPR/Cas9-based gene editing approaches in hPSCs would be advantageous. The successful candidate will be expected to have excellent interpersonal, written and communication skills,
and be able to work to a high standard.
We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a
competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and
development courses to support your personal and professional development.
We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions
complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research,
teaching and student experience.
To find out what makes the University of Sheffield a remarkable place to work, watch this short film:
and follow @sheffielduni and @ShefUniJobs on Twitter for more information.
Job tags
Salary
£37.1k - £39.35k per annum
