Vertex Pharmaceuticals
Location
Oxford, Oxfordshire | United Kingdom
Job description
Principal Automation Scientist page is loaded
Job Description
We are seeking a highly motivated scientist with expertise in automating biology, liquid handling and high throughput screening to join our High Throughput Biology group within our Integrative Biology department.
The Principal Automation Scientist is self-reliant with a formidable record of accomplishments, independently looking for opportunities to build and deploy automation solutions across a number of drug discovery projects. The Principal Automation Scientist innovates and leverages automation in areas of disease biology using patient relevant cellular models and appropriate readouts of the disease or target mechanisms under investigation, generating insights that influence research strategies. The role provides reliable, valuable advice to other research teams and departments on a regular basis, and exhibits an ability to make significant conceptual automation contributions.
T he successful candidate will automate the generation of high quality cellular screening reagents including multiple cell lines and iPSC derived organoids, and automate high throughput screens using these cellular reagents at scale. They will work with our automation engineer to develop and optimise assay protocols on robotic systems e.g. HighRes Cellario, ensuring optimal efficiency and performance. They will interact with other team members to miniaturise, increase the throughput of protocols and apply automation, develop and optimise liquid handling methods and support a range of workflows including complex cell culture, compound treatment, preparation of samples for endpoint analysis (e.g. flow cytometry, imaging). They will be able to t rain colleagues to use automation and instrumentation , e xplore new technology and robotic solutions w ork ing with automation engineers across our r esearch organization to share learnings and establish best practices .
The ideal candidate may have
Built innovative automation solutions to industrialize complex data rich higher throughput screens
Experience of adapting protocols to automation and support teams using automation
Ability to interact with vendors to maintain systems at peak performance
Experience of developing and optimizing complex protocols on liquid handling devices (e.g. Hamilton, Bravo, Biomek, Tecan)
Expertise in and ability to implement and troubleshoot automation scheduling software (Green Button Go, Cellario, or equivalent)
Experience in automating complex cell culture
Able to work in a team with good interpersonal and communication skills
A ttention to detail , good organizational skills and fully compliant with Vertex policies
Experience of building and leveraging state-of-the-art automation for high throughput screening an industrial setting
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Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected].
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) — a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational small molecule, cell and genetic therapies in other serious diseases where it has deep insight into causal human biology, including sickle cell disease, beta thalassemia, APOL1-mediated kidney disease, pain, type 1 diabetes, alpha-1 antitrypsin deficiency and Duchenne muscular dystrophy.
Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America. Vertex is consistently recognized as one of the industry's top places to work, including 13 consecutive years on Science magazine's Top Employers list and one of Fortune’s Best Workplaces in Biotechnology and Pharmaceuticals and Best Workplaces for Women. For company updates and to learn more about Vertex's history of innovation, visit or follow us on Facebook , Twitter , LinkedIn , YouTube and Instagram .
The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives.
Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.
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