Bioanalytical method development and method validation of LC-MS/MS methods for Analyte and metabolites in biological matrixes.
Subject sample analysis according to SOP/Protocol.
Bioanalysis of Drug metabolism studies including metabolic stability, Hepatocyte stability, metabolite identification (Phase-I, Phase-II), CYP inhibition, Log P and Log D, Blood Stability, Plasma protein binding, biorelevant media Stability, Permeability Study CACO2, MDCK, MDR1, and Solubility studies in In Vitro systems using LC-MS/MS analysis.
Provide inputs towards chromatographic and mass spectrometric advancement and challenges.
Troubleshooting of LCMSMS instrument in case of any malfunction.
Interact and communicate professionally with Service engineer in case of malfunction of instrument and also Application scientist for NEW assay development.
Operation calibration and maintenance of all lab equipment (LCMSMS, Analytical balance, pH meter, micropipette, etc.).
