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Deputy General Manager - Preclinical Pharmacology


Sun Pharma Advanced Research Company Ltd.


Location

Vadodara | India


Job description

This role will lead a team of researchers to support projects related activities pertaining to

in vivo

oncology for different modalities (small molecules, biologicals, etc.) entailing new model development; screening and interpretation of results, generation of new ideas and new target identification and validation. The role requires extensive cross – functional collaboration and liaising with internal and external stakeholders. Expertise in core preclinical oncology drug discovery and development is desired.

Key responsibilities of the role: Oversee

in vivo

screening experiments and generate repots in a timely manner Independently design and execute new experiments and develop CDX/PDX models and validate them Effectively coordinate inter-departmental communication to facilitate timely execution of tasks and data communication. Present key finding in project team meeting and to senior management Interact with external collaborators/CROs/Academic partners to provide high quality, timely and on-budget studies Mentor and train group members to facilitates their professional growth Generate new ideas: conduct and assist in target evaluations & due diligence on internal and external ideas Excellent interpersonal, written and verbal communication skills and the ability to work in team environment with passion and enthusiasm for pharmacology and drug discovery Desire and ability to work in a fast paced, cross-functional, flexible and team-oriented environment Aptitude for maintaining flexibility to respond to changing project priorities

Technical Skills: Deep understanding of drug discovery process and preclinical pharmacology assessments Thorough understanding and experimental experience in immuno-oncology is desirable Expertise with multiple and diverse molecular techniques for study of biomarkers in in vivo studies Hands on experience in CDX and PDX models to evaluate efficacy; molecular biology techniques - IHC, WB, FACS, RT-PCR, ELISA, imaging, etc. to assess biomarkers and translational relevance.

Educational Qualification & Work Experience A Ph.D./post-doc Oncology At least 12-14 years of experience in pharmacology in the drug discovery and development research division


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