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Principal Scientist Peptide Protein Chemistry


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Location

Us, 50250 | France


Job description

This BioPharma is a neurosciencefocused biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs but few options. We are dedicated to discovering and developing lifechanging treatments for patients with underaddressed neurological endocrine and psychiatric disorders. The companys diverse portfolio includes FDAapproved treatments for tardive dyskinesia Parkinsons disease endometriosis* and uterine fibroids* as well as clinical programs in multiple therapeutic areas. For three decades we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. *in collaboration with AbbVie

About the Role:

Seeking a highly motivated and talented peptide chemistry leader to join our new discovery peptide research group. The successful candidate will work on the design synthesis and characterization of novel peptides and peptide conjugates to discover nextgeneration peptidebased therapeutics. Your expert synthetic knowledge and proven design and synthetic accomplishments will enable you to have significant impact on Companys projects. This is an exciting opportunity to grow your career and help discover peptide therapeutics of the future.

Your Contributions (include but are not limited to):

  • Lead projects and teams towards agreed upon goals ultimately working towards clinical candidate peptide nomination
  • Design synthesize and characterize peptides small proteins and chemicallymodified analogs using stateoftheart synthesis bioconjugation purification analytical and biophysical techniques
  • Independent datadriven optimization of peptide SAR
  • Effective communication of scientific rationale results and interpretation at project team and departmental meetings contributing to strategic discussions.
  • Active collaboration and sharing of expertise with colleagues
  • Builds and enhances internal and external professional relationships
  • Aid in recruiting of peptide group scientists
  • Future management of more junior scientists

Requirements:

PhD in organic chemistry or related field with at least 5 subsequent years of experience in an industrial setting

Proficient in all aspects of modern peptide synthesis protein bioconjugation peptide and protein purification and analysis

Experience in optimizing and delivering peptideprotein conjugates as candidates for clinical trial

Strong publication record of accomplishment

Strong understanding of peptide and protein structure and associated biophysical techniques to assess structure stability and behavior in solution

Experience in bioconjugation timeextension and formulation strategies for peptides and proteins

Motivated to maintain a strong laboratory presence along with design and planning activities

Excellent interpersonal skills with strong oral and written communication abilities

Demonstration of crossfunctional understanding related to drug development

Assimilates data and research findings outside of our co. for application to new scientific projects

Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools

Prioritizes teamwork above all else

Exhibits leadership skill and ability typically leads lower levels and/or indirect teams

Excellent computer communications problemsolving and analytical thinking skills

Sees broader picture impact on multiple programs teams and/or departments

Ability to meet multiple deadlines across a variety of projects/programs with a high degree of accuracy and efficiency

position is located in San Diego CA and includes competitive base salary bonus full benefits and a full relocation (robust relocation package including help with real estate temporary housing and extra financial bonus)


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