Centre for Genomic Regulation
Location
Barcelona | Spain
Job description
The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
Chromatin modifications have been generally associated with the regulation of gene expression. However, recent reports have challenged this broad view of the role that chromatin may play. The successful candidate will participate in a project with the goal of further understanding how different chromatin features contribute to cell fate establishment and maintenance. The candidate will work with both publicly available and data generated in the lab on different dynamic models to uncover the role of chromatin modifications in these systems and to disentangle the relationship between histone modifications and gene regulation.
About the lab
The overarching theme of the research in our lab is the understanding of the information encoded in genomic sequences, and how this information is processed in the pathway leading from DNA to protein sequences. More specifically, we are interested in the epigenetic regulation of gene expression and RNA processing, the relationship between molecular phenotypes and higher order endophenotypes and organismal phenotypes, and the identification of functional regions on the genome of all living beings. Our group is mostly computational, and we do both large scale data analysis and development of methods, but it has also an important experimental component. We participate in many large scale international functional genomics projects, such as ENCODE, GTEx, BluePrint and others.
Whom would we like to hire?
Professional experience
Must Have
You have an excellent academic record, previous research experience and a strong commitment for scientific research
You have k nowledge of Molecular Biology and Computational Biology
You have f amiliarity with genomics / transcriptomics computational methods and data integration
Education and training
You hold a University Degree and a master's degree in biomedical / computational sciences within the European Higher Education System (minimum 300 ECTS) or an equivalent University Degree that allows to start a PhD thesis before the start of the work contract.
Languages
You are proficient in English
Technical Skills
You have s trong programming skills: C, python, and other scripting languages
You have s trong algorithmic and statistical skills and familiarity with the R package
You have f amiliarity with bioinformatics tools and HPC computing
Competences
You have h ighly developed organisational skills
You have the ability to interact with others, both with colleagues within the group and from other groups inside and outside the CRG
You have g ood (academic) writing and presentation skills
You are creative, motivated, curious and proactive
You have critical thinking
The Offer – Working Conditions
Estimated annual gross salary : Salary is commensurate with qualifications and consistent with our pay scales.
We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .
We offer and promote a diverse and inclusive environmen t and welcomes applicants regardless of age, disability, gender, nationality, ethnicity , religion , sexual orientation or gender identity.
The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
Application Procedure
A ll applications must include:
All applications must be addressed to Dr. Roderic Guigó and Dr. Sílvia Pérez-Lluch and be submitted online through the "Apply" button below.
Selection Process
Pre-selection : The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.
Interview : Preselected candidates will be asked to pass a written test. Those passing the thresholds will be interviewed by Dr. Roderic Guigó and the CRG Graduate Committee in September.
Offer Letter : Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.
Deadline : Please submit your application by March 14, 202 4.
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