Biologist, Biotechnologist as Scientist - Tumor Immunology (m/f/d)
Location
Unterschleißheim | Germany
Job description
CatalYm GmbH is a clinical-stage biotechnology company dedicated to advancing cancer treatment through pioneering Visugromab, a recombinant antibody targeting the immunosuppressive cytokine GDF-15. Under physiological conditions, GDF-15 is essential in feto-maternal tolerance and protection of injured tissues. In cancer, GDF-15 is markedly overexpressed across various tumor types, hindering the body's ability to mount effective immune defenses against tumors and contributing to resistance to treatment. Visugromab is designed to neutralize the activity of GDF-15, reinvigorate anti-tumor immune responses, and enhance the activity of cancer immunotherapy. In our commitment to advancing Visugromab, we're looking for a dedicated Associate Scientist to join our research team and contribute to making a difference for cancer patients. (Associate) Scientist (m/f/d) - Preclinical Tumor Immunology
(Associate) Scientist (m/f/d) - Preclinical Tumor Immunology
The selected candidate will be a member of the preclinical in vivo research team and will contribute to the advancement of our understanding of visugromab’s mechanism of action and the identification of novel drug combinations for cancer therapy.
Aufgaben:
- Plan in vivo pharmacology studies in rodents, incl. preparation of appropriate study protocols
- Interact with external service providers and ensure smooth and timely execution of in vivo studies, incl. contract management and scientific exchange
- Coordinate and oversee the shipment process for test reagents and in vivo study samples
- Evaluate study data and document results according to internal standards
- Perform ex vivo analyses of mouse tissues and serum samples (ELISA, multiplex cytokine/chemokine assays, SDS-PAGE, Western Blot, qRT-PCR)
- Plan, perform, and document immunological in vitro assays to complement the preclinical data package
- Provide scientific and technical expertise and support the team with scientific literature research
- Contribute to scientific publications and patent applications
- Actively participate in internal and external scientific meetings and present experimental results
Qualifikationsprofil:
- Ph.D., M.Sc., or comparable degree in biology, immunology, biomedicine, biotechnology, or related disciplines
- Minimum of 3 years related work experience, industry experience is a plus
- Knowledge of tumor immunology, immunology, cancer, immunotherapies, or related fields
- Experience with animal experiments, especially with mouse tumor models
- Experience in managing projects at external service providers
- Training in cellular and molecular biological techniques such as cell culture, cell isolation, multicolor flow cytometry, ELISA, Western blot, qRT-PCR, and cytotoxicity assays
- Familiarity with the software applications GraphPad Prism, FlowJo, and MS Office applications is desirable, knowledge in the field of statistical analysis is a plus
- Demonstrated ability to work independently, assume responsibility for tasks, and take initiative in proactively addressing challenges and seeking solutions
- A good command of written and spoken English, proficiency in German is a plus
- Strong aptitude for working in a team, good communication and organizational skills
- Excellent problem-solving abilities, attention to detail and adaptability
- A work permit for Germany is mandatory
Benefits:
- The opportunity to contribute to research directly impacting cancer therapy and clinical trials
- Comprehensive training to enhance your scientific, technical, and interpersonal skills
- A role in a pioneering environment as part of a dynamic biotech company on the rise
- A collegial atmosphere characterized by a driven and supportive team
- Opportunity for flexible work schedules and remote work arrangements, within the framework of company policies and dependent on project requirements
- A secure and permanent employment contract
Job tags
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