F. Hoffmann-La Roche Ltd
Location
Penzberg | Germany
Job description
A healthier future. It’s what drives us to innovate.
To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.
Creating a world where we all have more time with the people we love.
That’s what makes us Roche.
Your position and department
The position of Scientist Biomarker Discovery (m/w/d) is embedded in the biomarker discovery chapter at Roche Diagnostics R&D. This unit is focusing on the biomarker discovery for different fields of clinical application and disease areas and top-tier technology development. Biomarker candidates discovered are targets of prototype assay development for implementation in clinical study assessment.
Your work will focus on the following aspects
In the R&D group of biomarker discovery you will analyze large “-omics” datasets from internal and external sources. You will work at the leading edge of diagnostic biomarker science and support global units with innovative solutions in t he area of biomarker hypothesis generation applying various bioinformatics approaches.
Design and implementation of algorithms for processing multi-omics datasets like gene expression data, protein expression profiles as well as display or array based readouts and their analysis in disease specific manner
Elaboration of concepts for multi-omics data integration and establishment of machine learning based models as well as pipelines for biomarker discovery and leading and accomplishment of projects within broader disease-related cross-functional programs and moreover assessment and evaluation of cutting edge technological approaches for biomarker identification
Coordination of your approach with interdisciplinary project teams and experts from diverse subject areas as well as external partners (academia as well as companies)
Finally, you will be part of a highly motivated team having profound experience in the field of discovery defining targets for biochemical assay development and using state of the art methods, equipment and facilities
Who you are
You bring a doctorate and Post-Doc in bioinformatics or a similar area
Your experience and deep understanding of implementing disease biology, statistics, and requirements for experiments or clinical studies improving biomarker discovery design is of high value to us
You have excellent knowledge or experience in:
Programming or with large -omics bioinformatics tools, data annotation and curation
Applying, generating and adapting bioinformatics pipelines for the analysis of sequencing data from various technological applications of RNAseq (e.g. bulk, spatial, single cell, epigenetic or metagenetic) as well as proteomics and other single cellular approaches
Application of machine learning and multi-omics data integration methods
Translation of complex problems and gathered experience in workflow development
The following is particularly important to you in your work and in collaboration with others:
Cooperating with project members from diverse scientific backgrounds
Professional and personal development
Interdisciplinary and intercultural cooperation
Proactive working methods and passion for finding innovative solutions to scientific questions
Demonstration of personal flexibility and the capability to work independently
Fluent communication in English, German is not mandatory
This position is limited to the duration of 3 years.
Application documents
For the application process please add a letter of motivation and your updated CV. References and certificates are not required at this stage.
We look forward to receiving your application!
Do you need more support?
Our Talent Acquisition Team welcomes your questions. Please send an email to
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Roche at Penzberg, near Munich, employs more than 7,000 people. The site is one of the largest biotechnology centers in Europe and the only Roche site with research, development and production for both Pharmaceuticals and Diagnostics under one roof. From your beginning with Roche, our motivated team will welcome and support you. Numerous opportunities for personal development, flexible work hours, attractive compensation packages and special family assistance programs are available.
Roche is an Equal Opportunity Employer.
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